Side Effects of LATUDA

Ask Your Doctor About Possible Side Effects of LATUDA

Learning about possible side effects is an important part of taking any medication. For people taking Latuda® (lurasidone HCl), the side effects may differ. Your doctor can tell you what to expect when you’re taking LATUDA as your bipolar depression medication—both the side effects and benefits.

Once you have the complete picture, you and your doctor will be able to make important treatment decisions together. After all, no one knows your body better than you.

The side effects shown below are NOT a complete list. Please see additional Important Safety Information for a more comprehensive list.

Be aware of any possible side effects and work with your doctor to help manage them. Speak up if your medicine is not working or if you have any side effects. If you are starting to experience worsening of symptoms, don't be afraid to call your doctor.


Antidepressant medicines may increase suicidal thoughts or behaviors in some children, teenagers, and young adults within the first few months of treatment. Depression and other serious mental illnesses are themselves associated with an increase in the risk of suicide. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, especially sudden changes in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. Report any change in these symptoms immediately to the doctor. LATUDA is not approved for use in pediatric patients with depression.

The most common side effects of LATUDA

In clinical studies the most common side effects with LATUDA included:

  • Adults with bipolar depression: restlessness or feeling like you need to move around (akathisia); difficulty moving or slow movements; and sleepiness or drowsiness
  • Children (10 to 17 years) with bipolar depression: nausea; weight gain; and problems sleeping (insomnia)

This summary is not a complete list of side effects. Please see the Important Safety Information, including Boxed Warnings, below and on the following page, for a more complete list. Tell your health care provider if you experience any side effects while taking LATUDA.

You are encouraged to report side effects of prescription drugs to the FDA. Visit or call 1‑800‑FDA‑1088.